Tag archives: Veterinarian

Breeding Carriers of Canine Recessive Diseases- Why It Should be Considered

Breeding Carriers of Canine Recessive Diseases- Why It Should be Considered

The breeding of dogs identified as genetic carriers of recessive disease is a hotly debated topic in the canine breeding world with many breeders firmly entrenched in their own personal approach to the issue. With increasing regularity, dog breeders and their clients are bringing genetic questions (including those about breeding carriers) to their veterinarians under the assumption that most veterinarians would be up to speed on the current information and genetic testing available. Unfortunately, at Paw Print Genetics we occasionally speak to breeders whose veterinarians have given them advice about breeding carriers that may not be in the best interest of the kennel or the breed. Given the large number of variables and differences between the way kennels are operated and the recessive disease risks of individual breeds, there is not necessarily a breeding approach that would be appropriate in 100% of cases. However, understanding some guiding principles and the potential ramifications of doing so, can help a veterinarian advise their dog breeding clients in a way that will help them meet their goals without increasing the incidence of recessive diseases in a kennel or in the breed.

What is a “Carrier” of a Recessive disease?

As a quick refresher ...

Canine Genetics In Practice- A Veterinarian’s Role in Preventing Adult-onset Inherited Disease

Canine Genetics In Practice- A Veterinarian’s Role in Preventing Adult-onset Inherited Disease

Veterinarians examine, treat, and diagnose dogs with inherited diseases daily. Though treatments to fix some inherited disorders such as cryptorchidism and umbilical hernias are relatively safe and effective, rarely are the inherited disorders seen in practice remedied with a simple, relatively low-cost solution. In fact, in many cases of inherited disease, treatment options are extremely limited or non-existent. Therefore, an option to prevent these diseases before they occur would be preferable in most circumstances. Genetic disease testing made possible by the discovery of the causal mutations has become the best medicine to combat many inherited conditions.

Genetic testing of dams and sires has become commonplace in many dog breeds as breeders have recognized the power of identifying those dogs at risk of producing puppies with inherited diseases. Unfortunately, however, some breeders have been slow to adopt the routine use of genetic testing as they continue to rely on traditional selective breeding techniques. Limited by the inability to identify unaffected carriers of disease, selective breeding has historically proven relatively ineffective in the pursuit of large reductions in disease incidence.

Adult and late-onset inherited diseases pose an extra challenge in selective breeding because dogs become sexually mature before signs of the disease ...

Improving Client Experience and Clinical Outcomes with Canine Genetic Disease Testing

Improving Client Experience and Clinical Outcomes with Canine Genetic Disease Testing

The expanding role of the dog over recent decades as an anthropomorphized member of the modern American family has led to an increase in dog owners’ expectations of their veterinarians. With social media, where the old adages about the number of people a dissatisfied client will tell about their experience can be easily multiplied by a factor of hundreds, the pressure to meet client expectations is more intense than ever.

Far more actionable than the commonly used genetic testing for canine breed identification, canine genetic disease testing is an accurate and reliable tool to help veterinarians meet their clients’ expectations in new ways. Genetic testing for a variety of inherited diseases has become commonplace in the dog breeding community to help breeders produce puppies free of particular maladies. However, as we know, not every dog seen in practice is the product of two purebred parents which have been genetically tested and vetted to make sure they are a good genetic match. Having a solution to easily perform canine genetic disease testing for any dog in a clinical setting, no matter the breed, adds a level of sophistication and progressiveness to your practice which can also supplement and improve your overall ...

Paw Print Genetics Now Offers Veterinary Verification Option for Your Samples

Paw Print Genetics Now Offers Veterinary Verification Option for Your Samples

Paw Print Genetics understands that our customers know what’s best for their breeding programs and what they need from a laboratory. Our customers are the experts and that’s why we listen closely and ask questions. Doing so has resulted in Paw Print Pedigrees, a free website that Paw Print Genetics customers can use to promote their kennels and show off their health tested dogs. Another feature recently added is our Clear by Parentage program, which allows the breeder to get Clear by Parentage certificates on any pup resulting from health tested, parentage-proven parents. Because our customers asked for it, Paw Print Genetics now offers an optional, Veterinary Verification for samples collected by a veterinarian and submitted to us for testing.

Veterinary Verification is an optional and voluntary program offered by Paw Print Genetics that allows breeders to confirm the identity of their dog by having a veterinarian collect the sample and verify a permanent identifier for that dog (microchip number or tattoo). There is a simple form that must be completed by the veterinarian and this form must accompany the sample to the laboratory.

Having a verified sample may provide puppy buyers extra assurance that the test results they receive ...

Genetic Testing of the Symptomatic Dog

Genetic Testing of the Symptomatic Dog

It does not come as a surprise to veterinarians that many of the diseases they see in clinical practice have a hereditary component. If a genetic disease is amenable to treatment, veterinarians are typically well equipped to improve quality of life based upon their patient’s clinical signs. However, since clinical signs alone don’t always point to a specific definitive diagnosis, veterinarians treating inherited disease are often left with unanswered questions about the root cause of the medical problem. Paw Print Genetics offers genetic testing for over 140 different genetic diseases to help veterinarians shorten their list of differential diagnoses and identify the specific genetic mutation responsible for causing the clinical signs they are seeing, thereby, allowing for more specific therapies and recommendations to be made for the benefit of their patients.

Breed Specific Genetic Testing

Many inherited conditions seen in dogs are breed specific or have only been described in particular breeds or breed groups. For instance, one specific mutation in the canine HSF4 gene responsible for early-onset hereditary cataracts has only been described in the Australian shepherd and closely related breeds. Searching a specific breed or symptom on the Paw Print Genetics website will simplify the process of choosing ...

Integrating Genetic Testing Into Veterinary Practice- Mixed Breed or Pure Bred Pet Dogs

Integrating Genetic Testing Into Veterinary Practice- Mixed Breed or Pure Bred Pet Dogs

For many years, an extensive physical exam, fecal sample testing, vaccinations, and deworming have been the mainstays of new puppy veterinary visits. While all of these tried and true steps are crucial in making sure that a puppy is healthy and stays that way, advances in genetic testing technologies are now revolutionizing the veterinarian’s approach to addressing and anticipating potential health issues in young dogs. Though inherited diseases are seen by veterinarians on a frequent basis, many veterinarians do not realize that genetic testing for diseases is available or understand how clinically helpful testing puppies at their first visit can be. How often do you discuss puppy genetic testing with your clients?

How Can Genetic Testing Improve Veterinary Practice?

The implications that genetic testing results can have for a dog’s veterinary care vary by a specific disease’s age of onset, progression, and clinical signs. Early diagnosis of late-onset inherited diseases allows for your clients to become educated about what to expect and in some cases, take preventative measures and plan for life changes. Knowledge that a dog is at-risk for a particular late-onset disease also allows for early diagnosis and implementation of early treatment when possible. In some cases, clients ...

Integrating Genetic Testing Into Veterinary Practice- Breeding Dogs

Integrating Genetic Testing Into Veterinary Practice- Breeding Dogs

Most veterinarians are well aware that canine hip and elbow radiographs, echocardiograms, and eye examinations have become routine veterinary health clearances requested by dog breeders. The goal of these diagnostics is to help breeders to improve their blood lines and produce healthy puppies. However, unless you work in a practice with a heavy canine reproduction case load, it is likely that you are less familiar with the genetic testing employed by breeders, what genetic tests are available, and how the results of genetic testing can help your dog-breeding clients attain their goals. Now that genetic testing has become a common addition to other pre-breeding canine health testing, gaining an understanding of available genetic testing and offering a service to help your clients complete their genetic testing through Paw Print Genetics (PPG), may increase the value of your customer relationships and build client loyalty, while at the same time, fulfilling your veterinary goal to improve the quality and length of puppies’ lives. How often do you discuss genetic testing with your dog breeder clients?

Dog Breeding and Genetic Testing

Though vet school curriculums have historically addressed canine inherited diseases and treatments for these conditions, much less emphasis has been placed on ...

Preparing Your Pet for Fires, Tornados and Other Natural Disasters

Preparing Your Pet for Fires, Tornados and Other Natural Disasters

House fires, wildfires, tornados, hurricanes and other disasters can destroy a home and displace families in a matter of minutes. If you live in an area prone to the destructive forces of nature, having a plan can save the lives of both you and your family – including your pets.

In the case of a house fire, when seconds count, organization matters even more when it comes to saving your pets. July 15 is National Pet Fire Safety Day, and as such, we’re here to offer a few tips to help you prepare in the case of an emergency situation.

When Quick Exits are Required

First and foremost, you have to get to a safe place – and you have to take your pet with you. Don’t leave your dog behind to fend for itself or for first responders to rescue – they’ll likely be too busy saving human lives to take responsibility for your pet.

Depending upon the situation, those safe places could be very different – from the highest ground possible during a flood to an interior room or safe room during a tornado. During a house fire, evacuation is usually the best action, which makes organization very important ...

Canine Emergencies: First Aid Kits and Care

Canine Emergencies: First Aid Kits and Care

Paw Print Genetics recently attended the Washington State Search and Rescue Conference in Ellensburg, Wash. The conference provides educational classes for civilian search and rescue personnel, including canine teams.

While several canine-related classes were offered, including tracking, testing and meteorology, perhaps my favorite was the first-aid class offered by Dr. Michael Fuller, a 30-plus-year veterinarian at the local Ellensburg Animal Hospital. He covered a lot of material in the hour-and-a-half session, everything from must-have items in a first aid kit to broken bones. And while the class was devoted to SAR teams that are often far removed from help, the suggestions on what to pack make an excellent quick, easy-to-carry kit for travelers, hikers and hunters.

First, according to Fuller, nothing is more important than commonsense. The most well equipped first kit won’t do any good if you use it incorrectly. Second, many of the items found in a human first aid kit can be used in a canine first aid kit – including triple antibiotic ointment, eye wash, sterile bandages and wraps, pain relievers and anti-histamines.

First Aid Kits
Fuller recommended starting with a commercial first aid kit and then adding a few items to it. You should carry ...

Do you have a test to screen for hip dysplasia?

Do you have a test to screen for hip dysplasia?

Since I started my work with Paw Print GeneticsTM and began discussions with many in the canine community, I have been asked more about hip dysplasia (HD) than any other disease.  Perhaps it is due to the significant decrease in quality of life it can create for affected dogs or perhaps it is because historically, it has been one of the most extensively studied canine diseases.  Regardless of the reason, it is clear to me that dog owners and breeders are concerned about the disease and would love to see it eradicated.  Unfortunately, we may be years off from fully understanding all of the contributing causes and thus, preventing this often debilitating disease.

In the most basic sense, HD is simply a condition of loose hip joints, but it is the secondary consequences of these loose joints that cause the clinical condition we recognize in dogs.  In affected dogs, laxity in the hip joint leads to abnormal alignment between the head of the femur and the pelvic socket (acetabulum) that serves as the gliding surface for the head of the femur during movement.  This improper alignment leads to abnormal wear and tear of the ...