Paw Print Genetics is excited to tell you about 15 new tests that were just launched! Among these new tests are three new trait tests that cause light colored dogs in various breeds. These new traits are sable in Cocker spaniels, white in Alaskan and Siberian huskies, and cream in Australian cattle dogs. What’s super interesting is that these new tests all involved DNA changes in the E locus. Most are already familiar with the E (extension) locus, as DNA changes or variation in the MC1R gene inhibits the production of the black pigment, eumelanin, and allows the yellow/red pigment to show (phaeomelanin) and causes the coat color to be light, such as apricot in poodles, yellow in Labradors, and red in Irish Setters. For the specific breeds mentioned above, you can now test specifically for the Eh variation found in some sable Cocker spaniels, or the e2 variation found in cream colored Australian Cattle dogs, or the e3 variation found in Alaskan and Siberian huskies. For all other breeds, you can just continue to order the common E locus variant to find out if your dog carries for yellow. Remember, white/yellow/red ...
National Pet Day!
Our dogs, our cats, our birds. They are more than just pets – they are our family members! Today, April 11th, we celebrate National Pet Day. The ones who bring us joy, laughter, and even snuggles. What would we do without our pets? Although they may not be able to live forever, we can do our best to give them long and healthy lives. At Genetic Veterinary Sciences, Inc. (GVS), we provide resources to achieve optimal canine, feline and avian genetic health to do just this. We do this through the genetic testing that we have developed for dogs, cats and birds.
What is genetic testing?
Genetic testing allows us to look into the DNA of your pets to learn about the inherited diseases they may have. We can also genetically test to learn about traits your animal may carry for such as coat colors. Our company differs from others as we follow the standards and guidelines for canine clinical testing laboratories, based on human diagnostic standards. This means all of our testing is of the highest quality and accuracy possible.
Why should I test my pet?
A common response we receive when discussing the benefits of genetic health testing is ...
Paw Print Genetics Launches New Trait Tests
Paw Print Genetics is excited to announce that it has launched six new trait tests for coat color (Cocoa, ba allele of the B Locus, d2 allele of D Locus), coat length (Lh2, Lh4) and ‘weak’ furnishings (Fw allele). These tests compliment the other coat color and trait tests that PPG already offers and shows our dedication to providing the largest menu of genetic tests for dogs. The following tests can be ordered as individual tests or are now incorporated into the previously offered test. It is important to order only those tests that are applicable for your breed, so be sure to notice the breeds that can have this mutation, located in the parentheses in the name of the test. If you are unsure about ordering, please contact us as we are always happy to help you understand the usefulness of the tests that we offer.
Coat Length and Cocoa Coat Color for French Bulldogs
Prior to the discovery of the Cocoa mutation, many French Bulldogs had an untestable form of brown. Thanks to an international group of researchers, the DNA change (variant) responsible for the Cocoa coat color was identified. The ...
Happy New Year from Paw Print Genetics
2015 was a big year for Paw Print Genetics. We made improvements to our website for easier account management, launched new disease tests, coat colors and traits, and won our lawsuit over Labrador exercise-induced collapse (EIC), so that you have choice in testing laboratories.
Our account management system is the best in the industry, but we are always looking for new ideas. Some of the website improvements made in 2015 include the ability to hide dogs within your account, share dogs between accounts and move dogs to new accounts. What would you like to be able to do in your account? We continue to make improvements to our testing, reporting and website, all based on your input.
In early January, we launched several new, important disease tests including hereditary cataracts for Australian shepherds and related breeds and hereditary cataracts for French bulldogs and related breeds. We also launched two progressive retinal atrophies in the golden retriever and retinal dysplasia/oculoskeletal dysplasia in Labrador retrievers. We have many additional tests on our list to develop in 2016. We look forward to bringing you those tests throughout the new year.
Paw Print Genetics now offers 10 coat color tests and ...
Season's Greetings from Paw Print Genetics
This is a special time of year; the time of year when we reflect on all of the things for which we are thankful. Good health, warm houses and loved ones are just a few of the things that we can be thankful for throughout the year. Paw Print Genetics is very thankful and grateful for our customers, large and small. Without the responsible breeders and individuals who care deeply about canine health, we would not be here. We take pride in serving you the best way we know how.
Paw Print Genetics works very hard to provide you the best genetic testing and customer service in the industry. We are proud to provide you with so many little extras to help you better care for your dogs. Some of the little things that matter include online account management, providing you changes to your dog’s reports at no charge, as you select the best and register those for the future, and providing Paw Print Pedigrees so that you can show the world that you are a responsible breeder.
In addition to our customers, I am thankful for our amazing staff of molecular technologists, PhD geneticists and veterinarians that are dedicated to ...
Paw Print Genetics Can Help You Better Integrate Genetic Testing Into Your Veterinary Practice
Paw Print Genetics has begun a new series of blogs aimed at helping veterinarians integrate genetics into their practice. These blogs help illustrate how the veterinarian might include discussions about genetics during new puppy visits, while helping a breeder with their breeding program, or considering genetic causes in developing a differential diagnosis for symptomatic dogs.
Veterinarians can assist clients in receiving genetic services in several ways. First, the vet may simply provide the dog owner information about testing options and clarify any questions that they might have. Second, the veterinary staff assists the owner in setting up an individual account and performs the blood draw or cheek swabbing for the customer. In this case, the genetic results would be uploaded to the customer’s account and the customer would have direct access to the information. Third, the veterinary clinic can set up a master account on the Paw Print Genetics website. Each customer’s dog is entered into the master account as orders are placed. For each dog, there is a field that allows the clinic staff to enter the dog owner’s name and contact information. After testing, the genetic results are uploaded to the clinic’s master account and the ...
Who’s on First: Congenital, Adult-Onset, and Progressive Conditions
When it comes to diagnosing genetic conditions in dogs (or in humans), doctors use a variety of clues. One of those clues may not necessarily be what the physical symptoms are, but when did the physical symptoms start happening. Today’s blog focuses on the when, not the what, of genetic diseases. Although the when of genetic disease does not exclude the importance of what; when will be today’s topic. Now that I’ve thoroughly confused you and you may be thinking about the old slapstick comedy routine “Who’s on First” by Abbot and Costello, let’s get started.
“Congenital” is a term that often floats around the medical community when discussing disease symptoms. It simply means “present at birth”. This complicated word comes from the Latin root “congenitus”, which literally means “born together with”. Con – with; genitus – to bear, or beget. If a symptom or group of symptoms is seen right when a pup is born, it is congenital. When making a diagnosis of an inherited genetic condition, knowing the symptoms are congenital can shorten the list of what genetic condition may be the cause. Only recently has canine ...
Genetics 101: Dominant and recessive traits in your dogs
The field of genetics has progressed rapidly in recent years. Perhaps you’ve seen headlines about these top genetic topics in 2013. These stories show the importance of genetics and how it affects us as individuals and as a society. To understand the impact, though, one may need a review of Genetics 101: dominant vs. recessive disease traits.
In order for our bodies to work properly, our DNA must be coded in specific sequences. DNA sequences are grouped into units called genes, which tell our bodies what to make to build cells and metabolize nutrients. We are all a unique combination of re-shuffled genes from previous generations. Everything from eye, hair and skin color, muscle, bone, etc. is coded by genes. A mutation in a gene usually causes something to change and many of these changes can lead to disease. There are thousands of genes, and in humans, thousands of genetic disorders that result from mutations.
One way to classify genetic disorders is to group them by how they are inherited. With the exception of the sex chromosomes, X and Y, each of us has two copies of our genes. One comes from ...
No Dogs Allowed: Quality Testing Guarantee
Have you ever wondered what goes on in a genetic testing laboratory? What kinds of measures are taken to guarantee quality testing? For example, does the laboratory that you use have what is pictured - a clean room? What is a clean room and why should they have one? And why can’t you bring your dog directly to the laboratory for swabbing?
Paw Print Genetics has received a lot of questions about our testing quality and accuracy – and we love it! Ask away! We like to talk about our lab and the careful approach we take to testing to ensure that your results are reliable and accurate. Otherwise, what’s the point?
A genetic testing lab must have accurate and reliable results. They should have performed validation studies for each of the diseases and mutations that they offer. Does your testing lab provide you with the test’s sensitivity and specificity for the diseases you are concerned about? Have you asked for this?
During our validation studies, we assessed eight performance criteria for each test: accuracy, precision, analytical specificity, analytical sensitivity, detection limits, reportable ranges, reference intervals and robustness. For example, accuracy refers to getting the right results; whereas, precision refers to ...
The Tragedy of Canine Genetic Disease
Dedicated in loving memory of Rigel - the blue star Afghan - may his star burn brightly.
Many understand the "need for canine health testing". People will dutifully test their dog’s hips, eyes (CERF exam), maybe elbows, thyroid, knees and the one DNA test for the BIG recessive genetic disease that has been known to exist in their breed for years. This sequence is what they have been taught that they must do to be a responsible breeder by the forefathers in their breed clubs. But how much do people really understand the need for genetic testing?
What about uncommon genetic disease in the breed? Every individual carries recessive non-working or disease genes; many of which are uncommon and can run silently in the family for generations before two carriers are bred together and produce affected puppies. It has often been touted that one reason for inbreeding is to identify and weed out recessive disorders, but how often is this actually done? If the problem is uncommon and unknown, affected individuals, especially those that die young, can go undiagnosed, especially if each and every puppy is not extensively evaluated. So the problem occurs unrecognized, unidentified and ...