Tag archives: blood

The Veterinarian's Corner- Beyond von Willebrand Disease: Genetic Testing for Other Canine Platelet Disorders

The Veterinarian's Corner- Beyond von Willebrand Disease: Genetic Testing for Other Canine Platelet Disorders

Von Willebrand disease (vWD) is arguably the most well recognized canine blood clotting disorder. A common genetic mutation in the VWF gene (first described in the Doberman pinscher in 2001) has played a significant role in increasing the recognition of vWD as a cause of clotting problems in dogs1. Genetic testing for this mild to moderate platelet disorder, known as vWD type 1 (vWD1 or vWDI), has played an important role in assisting veterinarians in diagnosis and in assisting breeders in identification of non-symptomatic carriers of the mutation prior to breeding. Since that time, dozens of other breeds have also been found to be affected by the same mutation. Thus, solidifying vWD as a potential concern for many dog lovers. In addition, other genetic mutations in the VWF gene have also been associated with more severe forms of von Willebrand disease (type 2 and type 3) in some breeds.

Despite the important role of testing some breeds for the identified vWD1 mutation, it is also important to keep in mind that hemostasis is an incredibly complex process involving multiple physiologic steps and the interaction of many protein clotting factors, various cell types, and endogenous molecules. In some breeds, other ...

Breed of the Week: Deutscher Wachtelhund

Breed of the Week: Deutscher Wachtelhund

The Deutscher wachtelhund, or German spaniel, is a medium-sized, thick-boned, muscular gun dog with a thick wavy coat that protects it from briars and cold water. While they’ve been around since the 1700s, they’re a little-known versatile gun dog in both the United States and its home country of Germany.

In the U.S., the wachtelhund was recognized by the UKC in 1996, and the breed standard was published in 2004. The AKC is currently accepting applications for its Foundation Stock Service, which requires acceptance from a domestic or foreign registry. In the case of the wachtelhund, that registration comes from the German Wachtelhund Club, which oversees the Deutscher Wachtelhund of North America, and has very strict criteria for acceptance. In Germany, the wachtelhund has only been allowed to be owned by hunters, gamekeepers and foresters – few citizens even know of the breed.  

While the wachtelhund has a spaniel look (in both size and appearance), and they do flush feathered game, they are a versatile breed that is expected to hunt not just birds but also furred game such as rabbits and foxes – and even bigger game like stag and wild boar. They tend to air scent ...

My Dog’s Mouth Has Been Bleeding? What Could Be Wrong?

My Dog’s Mouth Has Been Bleeding?  What Could Be Wrong?

In my years as an undergraduate college student, struggling to make ends meet, I lived next door to a woman with an old, Labrador mix named Bubba.  By initial impression, he seemed to be a very normal, happy and well-socialized dog.  However, one day, during my daily greeting from Bubba, I noticed some blood around his mouth.  At the time, I was a biology major trying to wade through prerequisites for admission to veterinary school and I hadn’t yet been exposed to the world of clinical veterinary medicine.  So, when I saw the blood around Bubba’s mouth, I didn’t pay much attention.  I had seen blood in my own dog’s mouth on occasion after chewing on a toy or a bone and it never amounted to much.  So, my uninformed mind had little to worry itself about.  I later learned from Bubba’s owner that he had bled like this since he was young.  However, the owner had never taken Bubba to a veterinarian for a diagnosis and to this day I still don’t know what was wrong with him.  Though the memory of Bubba had ...