Archives for Dec. 17, 2014

Progressive Retinal Atrophy (PRA1): A Preventable Inherited Disease of the Papillon and Phalène

Progressive Retinal Atrophy (PRA1): A Preventable Inherited Disease of the Papillon and Phalène

With their picturesque appeal, predecessors of the modern day papillon (known as continental toy or Titian spaniels) were popular subjects for European painters between the 16th and 18th centuries. The popularity of these small spaniels with European aristocrats and royalty of the Renaissance period, led to their appearance in many paintings from the era. The iconic, longhaired “butterfly-like” ears, for which papillons are named, are obvious in these paintings though many of the portrayed dogs were of the drop-eared variety of the breed that today is known as the phalène. According to an article on the Papillon Club of America website, in the late 19th century erect ears became a more desirable trait with papillon fanciers and eventually the erect-eared variety obtained their current position as the more popular form of the breed. In addition to their beautiful physical attributes, in their modern form, well-socialized papillons are described as happy, playful and affectionate family members. Papillons are also often described as frequent barkers, making them great guard dogs. Despite their adorable personalities and good temperament, like other purebred dogs, the papillon is known to inherit some genetic diseases that could prevent this regal breed from reaching the ...

Leukocyte Adhesion Deficiency: A Preventable Inherited Disease of the Irish Setter

Leukocyte Adhesion Deficiency: A Preventable Inherited Disease of the Irish Setter

From a thorough mixture of spaniels, pointers, and other setter breeds, the Irish setter made its rise to popular gun dog status in the 18th century in its native homeland, Ireland. Though originally of the red and white color pattern (now called the Irish red and white setter), by the time the Irish setter made its way to North America, the solid red color most commonly associated with the breed had been established through selective breeding practices. Originally bred for their versatility in hunting game birds, by the mid 1900’s the Irish setter’s role in the field had greatly diminished despite their popularity in the show ring. Controversial, yet successful, efforts were taken to outcross the breed to red and white champion English setters in order to preserve and improve field varieties. The resultant field variety, often referred to as the Red setter, is unique in its hunting abilities and appearance when compared to American show varieties of the Irish setter. However, the field variety still falls under the Irish setter name in the US.

Unfortunately, at some point during the breed’s development, a spontaneous mutation in the ITGB2 gene occurred in a single Irish setter. A portion of ...