Progressive Retinal Atrophy, Syndromic Retinal Degeneration (Shetland Sheepdog Type) is an eye disease affecting dogs. Affected dogs begin showing clinical symptoms related to retinal degeneration at around 6 to 10 years of age, though age of onset can vary. Initial clinical signs of progressive retinal atrophy involve changes in reflectivity and appearance of a structure behind the Retina called the Tapetum that can be observed on a veterinary eye exam. Progression of the disease leads to thinning of the retinal blood vessels, signifying decreased blood flow to the retina. Affected dogs initially have vision loss in dim light (night blindness) and loss of peripheral vision, which may progress to complete blindness. In addition to progressive retinal atrophy, affected dogs may show other clinical signs of variable severity including an upturned nose, dental abnormalities, an abnormal coat, kidney, disease, and obesity, However, each affected dog may develop a unique combination and severity of clinical signs.