Bernard-Soulier Syndrome is an inherited bleeding disorder affecting cocker spaniels. Affected dogs typically present between 2 to 4 years of age with variable signs of bleeding. Commonly, this will be prolonged bleeding and formation of a hematoma, or large blood clot, after a routine blood draw during a veterinary exam. Other signs can include episodes of bleeding in the mouth around the gums and nosebleeds. Veterinary findings of dogs affected with Bernard-Soulier Syndrome include variable to low platelet and red blood cell counts along with abnormally large Platelets seen during a microscopic exam of a blood sample. Severe, and sometimes life threatening, bleeding can occur in response to trauma or during routine surgery of these dogs. Whelping may result in severe episodes in female dogs. Treatment is mostly supportive but may require one or more blood transfusions depending on the severity of the episode. With appropriate management, these dogs can experience a good quality of life.