Tag archives: trapped neutrophil syndrome

Paw Print Genetics is a proud sponsor of the US Border Collie Handlers Association. With their Sheepdog Finals next month, it is a good time to think about genetic issues and whether to breed your dog.

Although generally considered a relatively healthy breed, like other purebred dogs, the border collie is at risk to inherit several genetic diseases. Testing your dog prior to breeding prevents the disease through avoidance of producing puppies at-risk. This brief article describes a few of the diseases that can currently be tested for in border collies.  Click here to find a complete list of tests for border collies.

Collie Eye Anomaly (CEA) can vary from mild to severe; mild cases have normal vision, while severely affected dogs can have retinal detachments, malformation of the eye, and blindness. Unfortunately it is not possible to predict the severity of clinical signs based upon the severity of an affected parent. About 2% of border collies tested at Paw Print Genetics are affected with this disorder.

Trapped Neutrophil Syndrome (TNS) is a disease of the immune system that prevents affected dogs from producing an adequate amount of neutrophils (a type of white blood cell).  Affected dogs commonly present at ...

If you are a dog owner that values intelligence and obedience above all else when choosing a dog, it’s likely you are familiar with the border collie. This hardworking canine breed who received its name from its likely place of origin along the border of England and Scotland, has historically been bred for working ability above all and is widely regarded as one of the most intelligent breeds in the world. Though generally considered a relatively healthy breed, like other purebred dog breeds, the border collie is known to inherit several genetic diseases; some of which are known to be caused by specific genetic mutations. Discovery of the specific mutations responsible for genetic diseases allow laboratories like Paw Print Genetics to develop tests to identify dogs that carry the mutation. This information allows breeders to selectively breed these carrier dogs to dogs that are clear of the mutation in order to avoid producing puppies with these diseases. Three specific inherited diseases are listed on the Canine Health Information Center (CHIC) website as optional recommended tests for the border collie. Testing for these diseases is available from Paw Print Genetics:

Collie Eye Anomaly

One of the biggest inherited disease concerns for ...