Tag archives: dogs

Fall Safety for You and Your Pup

Fall Safety for You and Your Pup

Fall brings some wonderful changes; brisk evening walks with your dog, autumn decorations, curling up on the couch to watch your favorite Halloween flicks to name a few. With the changing of the seasons comes some notable adjustments for your dog too. Below are a few things to help you and your dog prepare for the upcoming autumn season.

Keep an Eye Out for Wildlife

Be extra vigilant this time of year of your dog’s off leash whereabouts. If you live in a more rural area where wildlife is prominent, it may be second nature to keep your eyes peeled for deer, moose, coyotes or even bear. Don’t forget about the smaller animals like porcupine and skunks, all very busy with their winter preparations. These animals could pose unwanted threats to your canine.

Cooler Temperatures

Colder temperatures and shorter days often mean less time spent outside, which could decrease the amount of exercise your dog is getting. This could be especially perilous on older dogs with arthritis. Protexin Veterinary recommends short and consistent exercise for arthritic dogs, if possible, such as shorter walks multiple times a day rather than long winter walks. Additionally, moist heat therapy can decrease pain and ...

Does the same mutation always cause disease?

Does the same mutation always cause disease?

Paw Print Genetics is often asked if the same mutation always causes genetic disease, especially when the mutation is identified in a breed different from that originally investigated.  The answer is not simple.  For many of these types of genetic questions, I go back to my ‘human’ roots as a human geneticist.  Because more than 4,500 diseases and their genetic causes are known, human genetics can shed considerable light on problems just beginning to be investigated in dogs.

Currently, there are about 185 known mutations in dogs, with about 150 that cause disease and another 30 or so that cause traits such as coat color or coat length.  In dogs, these disease-causing mutations have been narrowly defined to certain breeds or certain clinical features (phenotypes), but is this always the case?

In human genetics, anything imaginable has been described. Certainly, there are diseases that are caused by single mutations; in this case, one mutation causes one disease.  But there are many examples of multiple mutations in one gene causing one disease and examples of multiple mutations in multiple genes causing one phenotype (one disease).  Likewise, there are many examples of the same exact mutation ...