Tag archives: Hip Dysplasia

Understanding complex inherited diseases in your dog

Understanding complex inherited diseases in your dog

When we look at the vast majority of genetic tests currently available for canine inherited diseases, we find a large number of diseases that can be predictably diagnosed with our current technology. For most of the available canine genetic tests, dog breeders understand that there are three commonly used designations applied to a dog for any given inherited disease; normal, carrier or affected. By knowing the way a disease is inherited (recessive vs dominant vs X-linked) and the number of copies of a mutation present in an individual, genetic testing laboratories like Paw Print Genetics can give predictable information about these diseases because they have a clear, 100% correlation between the cause and the illness. 

Unfortunately for dog breeders, inheritance is not always as clear cut as a simple recessive or dominant pattern. In fact, the diseases with a clear-cut inheritance pattern likely only make up a small percentage of the diseases with inherited components. Some of the most frustrating diseases for dog breeders and geneticists are those which pose an increased risk by the combined effects of multiple genetic mutations and/or environmental conditions. In these multifactorial diseases, rather than a 100% correlation between a singular genetic mutation ...

Which Dog Food to Feed Puppies?

Which Dog Food to Feed Puppies?

Puppy-formula foods have been around for a long time. Theories, myths, personal beliefs and veterinarian recommendations concerning them began to form about 31 seconds after they hit store shelves. This mass of information and misinformation can make it confusing for a puppy owner to know what to feed and when to switch a puppy to an adult formula.

When my dogs were young, a popular theory was to switch a dog off of a puppy formula at around six months of age. It was believed that puppy formulas were too hot and caused bones to develop too fast. I switched both dogs, the lazy bulldog and active Labrador, to performance formulas at about that age. Both developed well and with no issues. But was it the right thing to do and does the advice still apply?

It turns out that a ton of research and changes have taken place around puppy formulas in the last 10 to 15 years, and that’s always good news – for knowledge, whether it proves or disproves your position, is a means to a better end.

“The myth of switching a puppy to adult food early persists to this day. It started at a time ...

Breed of the Week: Mastiff

Breed of the Week: Mastiff

Large and imposing, the mastiff is a docile giant, despite its use throughout history in warfare, bear baiting and utilization as a guard dog. It’s also an ancient breed that has been a part of the foundation for several breeds of dog.

One of the largest dogs registered by the AKC, the mastiff should stand at least 30-inches tall at the shoulder (females at least 27-½ inches) and can weigh up to 250 pounds without being overweight. The one-time world record for heaviest dog belonged to a mastiff named Zorba, who weighed a massive 343 pounds and stood 35-inches tall.

Large mastiff-like dogs appear in artwork dating to 6th Century BC (and perhaps even earlier), and throughout history the large dogs have been used for fighting and guarding. From lions, tigers, bears and gladiators to use in war by the Britons and Romans, mastiffs fought ferociously. However, as vicious as they were in battle, they were just as gentle with and protective of their owners. It’s been noted that in battle, mastiffs would fight the enemy, but seemingly knew for which side they fought – and when the battle was over, they would return to a docile state. If ...

Do you have a test to screen for hip dysplasia?

Do you have a test to screen for hip dysplasia?

Since I started my work with Paw Print GeneticsTM and began discussions with many in the canine community, I have been asked more about hip dysplasia (HD) than any other disease.  Perhaps it is due to the significant decrease in quality of life it can create for affected dogs or perhaps it is because historically, it has been one of the most extensively studied canine diseases.  Regardless of the reason, it is clear to me that dog owners and breeders are concerned about the disease and would love to see it eradicated.  Unfortunately, we may be years off from fully understanding all of the contributing causes and thus, preventing this often debilitating disease.

In the most basic sense, HD is simply a condition of loose hip joints, but it is the secondary consequences of these loose joints that cause the clinical condition we recognize in dogs.  In affected dogs, laxity in the hip joint leads to abnormal alignment between the head of the femur and the pelvic socket (acetabulum) that serves as the gliding surface for the head of the femur during movement.  This improper alignment leads to abnormal wear and tear of the ...