Author archives: Lisa Shaffer

One of the best compliments that a company can receive is when a customer places another order after experiencing that company’s service. An even better compliment is when a customer refers that business to a friend or colleague. When we refer a friend to a business, we are putting our ‘stamp of approval’ on that business and putting our reputation on the line too. We hope that the company will provide that excellent customer service every time so that our friend doesn’t blame us if things go wrong. That is why referrals are so valuable to a company and why excellent customer service should be every company’s number one priority.

What constitutes excellent customer service? This may include an informative and easy to use website interface, a friendly human voice when the company answers the phone, the outstanding quality of the service they provide, and its caring interactions with the customer long after the service has been completed. When was the last time you ordered something and didn’t receive an email confirmation or reply that your precious purchase was on its way? The communication that a company has with its customer says a lot about the way it conducts its ...

Have you ever wondered what goes on in a genetic testing laboratory? What kinds of measures are taken to guarantee quality testing? For example, does the laboratory that you use have what is pictured - a clean room? What is a clean room and why should they have one? And why can’t you bring your dog directly to the laboratory for swabbing?

Paw Print Genetics has received a lot of questions about our testing quality and accuracy – and we love it! Ask away! We like to talk about our lab and the careful approach we take to testing to ensure that your results are reliable and accurate. Otherwise, what’s the point?

A genetic testing lab must have accurate and reliable results. They should have performed validation studies for each of the diseases and mutations that they offer. Does your testing lab provide you with the test’s sensitivity and specificity for the diseases you are concerned about? Have you asked for this?

During our validation studies, we assessed eight performance criteria for each test: accuracy, precision, analytical specificity, analytical sensitivity, detection limits, reportable ranges, reference intervals and robustness. For example, accuracy refers to getting the right results; whereas, precision refers to ...

Rickie Roo is an agility dog, a service dog and a roving reporter for the United States Dog Agility Association. She is well known in the sport of agility and in the rat terrier community. On October 12^th, 2013, Roo unfortunately had to have emergency surgery because of a luxated lens in her left eye. Primary Lens Luxation, or PLL, is a condition that can happen in many breeds including American Eskimo dog, American hairless terrier, Australian cattle dog, border collie, bull terrier, Chinese crested, Jack Russell terrier, jagdterrier, Lakeland terrier, Lancashire heeler, miniature bull terrier, Norwich terrier, Parson Russell terrier, Patterdale terrier, rat terrier, Russell terrier, Sealyham terrier, Teddy Roosevelt terrier, Tenterfield terrier, Tibetan terrier, toy fox terrier, Volpino Italiano, Welsh terrier, wire fox terrier, Yorkshire terrier.

Lens luxation can happen suddenly and when it occurs, needs to be surgically corrected as soon as possible to try to minimize any loss of sight. Luckily, Rickie Roo's luxated lens was caught very early by her owner, Deborah Davidson Harpur. Thanks to early intervention, Rickie ...

Degenerative myelopathy (DM) can be a devastating disease. Some breeds with this disease will lose the ability to walk in their later years – certainly after the age most dogs are bred. The mutation has been found in more than 70 breeds, which indicates that the original mutation might have occurred hundreds or thousands of years before many of the modern dog breeds emerged.

However, the frequency of the mutation varies between breeds and certainly the risk of developing the clinical disease seems quite distinct and breed-specific. For example, the frequency of carriers and homozygous mutation (affected) dogs in the Kerry blue terrier is about 52%(1), while carriers and affected dogs make up 91% of Pembroke Welsh corgis in Japan (2). Although wire fox terriers have a similar combined carrier and at-risk frequency of 90%, none have ever developed the clinical signs of DM (3).

In a 2001 study by Moore et al., German shepherd dogs had nearly twice the risk for death associated with spinal cord diseases, compared with Belgian shepherd dogs among military dogs (4). Although we don’t know for sure if the spinal cord disease was DM, certainly DM is one of the more common causes of this type of disorder ...

After extensive laboratory validation, Paw Print Genetics has launched 29 new breed-specific tests, bringing the total number of tests offered to 115.  This is one of the largest menus offered by any canine genetic testing laboratory in the world.

Among the new tests are diseases that no other laboratory offers in North America are multifocal retinopathy in the American bulldog, myotonia congenita in the Australian cattle dog, neuronal ceroid lipofuscinosis in the Australian shepherd and dachshund, hemophilia B in the beagle, copper storage disease in the Bedlington terrier, complement 3 (C3) deficiency in the Brittany, ichthyosis in the golden retriever, inherited myopathy in great Dane, startle disease in Irish wolfhound, and severe combined immunodeficiency (SCID) in Russell terrier, just to name a few.

Search our website to find more new tests for your favorite breed or the specific diseases that most concern you.

Paw Print Genetics offers three approaches to testing depending on whether you are screening for potential carriers or testing for affected dogs: 

In the first approach, choose only those diseases that concern you; choose one or more tests.

For the second approach, choose the breed-specific panel that has been carefully selected based on the medical ...

Paw Print Genetics is committed to excellence in customer service. To that end, we are reaching out to our potential customer base by providing seminars to various breed, specialty and community clubs, becoming involved in individual breeder’s breeding programs and attending dog shows.  We attended the Rose City Classic dog show in Portland, Ore in January and talked with hundreds of attendees that were concerned about the genetic health of their dog.  The breeders and dog owners expressed the desire to do informed breeding whereby they use genetic information to avoid producing puppies with inherited disease and eventually “breed out” the genetic diseases to produce healthier lines.

We have provided seminars on genetics to several clubs in the Spokane, Wash area including the Inland Empire Collie Club, Panorama Poodle Club of Mt. Spokane, and the Inland Empire Kennel Association.  We are delighted to provide these presentations as it gives us an opportunity to interact with club members and really understand their needs and concerns regarding inherited genetic disease.

This week, we will be at the Spokane Kennel Club dog show at the Spokane County Fairgrounds, Friday-Sunday, May 24-26.  Please stop by our booth to talk about ...

I recently overheard two people discussing the cost of raising a dog and genetic testing came up. One comment was: “Do you want to pay now for a healthy puppy or pay a vet later?”. She was referring to the cost of the testing versus the cost of paying for the long-term healthcare of a dog with an inherited disease. 

In actuality, the cost of genetic testing may be less than the cost you would pay for a tooth cleaning or other routine, preventative care for your dogs. However, the genetic testing will last a lifetime and shouldn’t have to be repeated. Knowing the genetic profile of your dog will help you plan on whether you put the cost and time into training the dog and whether you eventually breed your dog. Genetic testing can improve the value of your breeding program by insuring the buyers that you have taken an active role in reducing the known genetic diseases in your lines.

Let’s take an example and walk through the health issues and costs. Hyperuricosuria, also known as urolithiasis, is a disease that affects at least 14 different breeds of dogs. Affected dogs develop bladder stones that ...

On April 30th, you will be able to order genetic testing for your dogs from Paw Print Genetics^TM. Before we could open our doors for clinical testing, we had a lot of work to do, work that involved my entire family and our extraordinary staff.  We had to build an entire laboratory from the ground up. Part of that process was validating our tests, which, as I’ll explain, is an important and necessary step – and one that involved many of you. 

After more than 20 years of working in human genetic diagnostic testing, I decided to use these skills to improve genetic testing for inherited canine diseases. We are so grateful for the support of the community of dog owners and breeders who participated in our validation studies from December 2012 through March 2013. As unknowns in this industry, we appreciate your trust that we were doing the right thing with your dog’s DNA.

We set up our laboratory, designed our tests and conducted our validation as if Paw Print Genetics were a human diagnostic laboratory. This means that we have all of the validation documentation that would be required if we were regulated by ...

Paw Print Genetics^™ is a clinical laboratory dedicated to screening and diagnosis of genetic diseases and carrier states for all dogs. In deciding to start my second company, I engaged the help of my family members. My husband needed to be agreeable to investing (emotionally and financially) in another (yes, another) clinical laboratory. But this time, it would be ours and we could make the decisions, good or bad; we would be responsible for its successes and possible failures. After convincing him that Paw Print Genetics^™ is a great idea, we started doing our homework. It is important to know the market. Our market is dog lovers; not a small market. They include owners, breeders, trainers, veterinarians and all the dogs that they breed, train and sell. Every dog deserves optimal genetic health.

Next came the science. Our staff spent months identifying the known genetic mutations in dogs and developing tests to accurately identify whether a dog is normal, a carrier or affected with these diseases. Some may ask “What does a human geneticist know about canine genetics?” Compared to the human medical literature, I was surprised how little is known about canine genetic diseases. The opportunities to make a ...

Maybe your Doxie has Narcolepsy. Narcolepsy is an inherited condition known to affect Dachshunds. Narcolepsy is a disorder that affects a dog’s ability to stay awake for an extended period of time. Dogs with the inherited form of narcolepsy typically show signs of the disorder between one to six months of age. Affected dogs will fall asleep faster than normal dogs and appear sleepy more frequently. Episodes of narcolepsy tend to occur with positive stimulation like play or food. The affected dog may appear to collapse to the ground with a sudden loss of muscle tone but does not typically lose awareness. Symptoms do not progress over time and do not have other associated health problems.
Genetic testing of the HCRTR2 gene in Dachshunds will reliably determine whether a dog is affected with narcolepsy. Because narcolepsy is inherited in an autosomal recessive manner, the breeding of two carrier dogs has a 25% risk of producing affected pups. Testing is available from Paw Print Genetics^™ to determine the genetic status of your Dachshund. It is recommended that carriers with this mutation are not bred to avoid affected pups.