Archives for January 2015

Retinal Dysplasia/Oculoskeletal Dysplasia 1 (RD/OSD1): A Preventable Inherited Disease of the Labrador Retriever

Retinal Dysplasia/Oculoskeletal Dysplasia 1 (RD/OSD1): A Preventable Inherited Disease of the Labrador Retriever

Thanks to our loyal and dedicated clients, Paw Print Genetics continues to increase test offerings in 2015! To start our year off right, we released DNA profiling and parentage testing, seven long-awaited canine coat color tests, and four tests for other specific traits of the hair coat and tail. In addition, Paw Print Genetics continues to expand upon the largest canine inherited disease testing menu in North America by releasing 10 new inherited disease tests. One newly added test that will make many Labrador retriever owners happy is the test for an inherited disease known as retinal dysplasia or the more apt term, oculoskeletal dysplasia (often written as retinal dysplasia/oculoskeletal dysplasia 1 or abbreviated, RD/OSD 1). In March of 2014, RD/OSD 1 became a little more personal for Paw Print Genetics when we had the honor of meeting Frank, an adorable, blind RD/OSD 1 affected Labrador retriever living at the Double J Dog ranch in Hauser Lake, Idaho. We are excited to launch a test that allows breeders of sweet dogs like Frank to produce puppies free of this severe and challenging disorder!

RD/OSD 1 is a genetic disease of collagen caused by a mutation ...

Avoiding An Improper Canine Hair Coat Through Genetic Testing

Avoiding An Improper Canine Hair Coat Through Genetic Testing

Selective breeding for particular behavioral and physical characteristics has made the domestic dog one of the most fascinating case studies in species domestication. The massive amount of diversity that humans have bred into their canine companions is unmatched by other species, domestic or otherwise. It is fun to imagine how unusual it would seem if humans were routinely as physically diverse as Chihuahuas and mastiffs!

One trait that has been selected for in some dog breeds is a trait known as “furnishings”. For the uninformed, furnishings are a trait marked by a wiry hair texture as well as increased hair growth on the face and legs. This trait is important to some breeders as it is associated with the presence of a canine moustache and long eyebrows which are listed as breed standards for some breeds. Dogs of these breeds that are born without furnishings are often said to have been born with an “improper coat” (a term frequently used by breeders). In 2010, a mutation in the RSPO2 gene was discovered to be responsible for the presence of furnishings in the Portuguese water dog. Since then, tests for this trait have been developed allowing for discovery of the same ...